| Texans +2.5 at Jaguars 42.5 | | Bears -1.5 at Falcons 52.5 | | Panthers -3 at Eagles 39.5 | | Ravens -3 at Browns 39.5 | | Saints -1.5 at Giants 46.5 | | Steelers -2.5 at Buccaneers 38.5 | | Jets +7.5 at Patriots 43.5 |
| | Titans +7 at Colts 44.5 | | Cardinals +12.5 at Rams 51.5 | | Bills -5.5 at Raiders 53.5 | | Chargers +7.5 at Chiefs 40.5 | | Cowboys +1.5 at Packers 53.5 | | Commanders +7.5 at 49ers 52.5 |
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